Christina Aguilera performs "Ain't No Other Man"

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John Shearer

Andrew Panay, Peter Abrams and Robert L. Levy, producers, and Dav...

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Brandon Routh, Kate Bosworth and Kevin Spacey, presenters

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Cee-Lo (center) and Gnarls Barkley perform "Crazy"

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Cee-Lo of Gnarls Barkley performs "Crazy"

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Christian Bale, winner of Best Hero for "Batman Begins"

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Christian Bale, winner of Best Hero for "Batman Begins"

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Christian Bale, winner of Best Hero for "Batman Begins" (center),...

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Christina Aguilera performs "Ain't No Other Man"

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Christina Aguilera performs "Ain't No Other Man"

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John Shearer

Danger Mouse (2nd from left) and Cee-Lo (3rd from right) of Gnarl...

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Danger Mouse (left) and Cee-Lo (2nd from right) of Gnarls Barkley...

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Danger Mouse (right) and Gnarls Barkley perform "Crazy"

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John Shearer

Danger Mouse of Gnarls Barkley performs "Crazy"

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Davey Havok of AFI performs "Miss Murder"

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David Dobkin, director of "Wedding Crashers," winner of Best Movi...

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Eva Mendes and Justin Timberlake, presenters

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Hunter Burgan, Jade Puget, and Davey Havok of AFI perform "Miss M...

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Jake Gyllenhaal, winner of Best Kiss for "Brokeback Mountain"

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Jake Gyllenhaal, winner of Best Kiss for "Brokeback Mountain"

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Jake Gyllenhaal, winner of Best Kiss for "Brokeback Mountain"

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Jamie Foxx

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Jessica Alba, host

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Jessica Alba, host

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Jessica Simpson and Dane Cook introduce AFI

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Jessica Simpson and Dane Cook introduce AFI

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Jim Carrey accepts the MTV Generation Award

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Jim Carrey accepts the MTV Generation Award

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Justin Timberlake, presenter, and Jake Gyllenhaal, winner of Best...

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Justin Timberlake, presenter, and Jake Gyllenhaal, winner of Best...

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Sacha Baron Cohen as "Borat"

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Sacha Baron Cohen as "Borat" introduces Gnarls Barkley

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Steve Carell, winner of Best Comedic Performance for "The 40-Year...

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Adam Carson and Davey Havok of AFI perform "Miss Murder"

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Adam Carson of AFI performs "Miss Murder"

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Andrew Panay, Peter Abrams and Robert L. Levy, producers, and Dav...

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Anna Faris and Amanda Bynes, presenters

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Brandon Routh, Kate Bosworth and Kevin Spacey present the Best He...

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Brandon Routh, Kate Bosworth and Kevin Spacey, presenters

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John Shearer

Cee-Lo of Gnarls Barkley performs "Crazy"

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John Shearer